Adamax

A synthetic nootropic peptide and a longer-acting analog of Semax (itself an ACTH(4-10) fragment analog), modified with an N-acetyl group and a terminal adamantane group to improve stability and extend its duration of action. Not an approved drug. Like Semax, it is studied for its modulation of the melanocortin system and of BDNF/TrkB neurotrophic signaling; the terminal modifications are intended to extend its half-life to several hours versus roughly 30–60 minutes for Semax.

Cognition, memory, focus and attention, neuroprotection and neuroplasticity pathways — explored in the same research context as Semax, with a longer duration of action.

Lyophilized. Reconstitute with bacteriostatic water per the general reference below.

General reconstitution & storage reference for lyophilized peptides:

1. 1Reconstitute with bacteriostatic water (0.9% benzyl alcohol) rather than plain sterile water — the preservative meaningfully extends usable shelf life.
2. 2In bacteriostatic water, refrigerate at 2–8°C, typically usable for ~28–30 days. In plain sterile water (no preservative): 7–14 days.
3. 3Lyophilized (unmixed) vials are stable at refrigerated or, for some peptides, frozen temperatures for extended periods prior to reconstitution.
4. 4Avoid repeated freeze-thaw cycles, direct light/UV exposure, and heat — these are the primary drivers of peptide degradation.
5. 5Reconstitute gently: inject the water down the inside wall of the vial and swirl — don't shake, which can denature the peptide structure.

As a newer research compound, human safety data is limited. Standard research-handling cautions apply.

• Research literature — Semax / ACTH(4-10) analogs